Article
Longitudinal follow-up of HPV16 sequence after cervical infection: Low intrahost variation and no correlation with clinical evolution.
Journal of medical virology - 1 Nov 2022
Debernardi Alice, Valot Benoit, Almarcha Julien, Guenat David, Hocquet Didier, Algros Marie-Paule, Riethmuller Didier, Ramanah Rajeev, Mougin Christiane, Prétet Jean-Luc, Lepiller Quentin
Abstract excerpt
Human papillomavirus (HPV) 16 exhibits different variants that may differ in their carcinogenic risk. To identify some high-risk variants, we sequenced and compared HPV16 whole genomes obtained from a longitudinal cohort of 34 HPV16-infected women who had either spontaneously cleared their infection (clearance group or "C"), or developed cervical high-grade lesions following a viral persistence (group persistence...
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