Article
Intra-host sequence variability in human papillomavirus.
Papillomavirus research (Amsterdam, Netherlands) - 1 Jun 2018
Dube Mandishora Racheal S, Gjøtterud Kristina S, Lagström Sonja, Stray-Pedersen Babill, Duri Kerina, Chin'ombe Nyasha, Nygård Mari, Christiansen Irene Kraus, Ambur Ole Herman, Chirenje Mike Z, Rounge Trine B
Abstract excerpt
Human papillomaviruses (HPVs) co-evolve slowly with the human host and each HPV genotype displays epithelial tropisms. We assessed the evolution of intra HPV genotype variants within samples, and their association to anogenital site, cervical cytology and HIV status. Variability in the L1 gene of 35 HPV genotypes was characterized phylogenetically using maximum likelihood, and portrayed by phenotype. Up to a...
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