Article
ctDNA as a biomarker of progression in oesophageal adenocarcinoma.
ESMO open - 1 Jun 2022
Bonazzi V F, Aoude L G, Brosda S, Lonie J M, Patel K, Bradford J J, Koufariotis L T, Wood S, Smithers B Mark, Waddell N, Barbour A P
Abstract excerpt
BACKGROUND: The incidence of oesophageal adenocarcinoma (OAC) is rapidly increasing and despite improvements in treatment, the 5-year survival rate remains poor. Prognostic biomarkers that address the genomic heterogeneity in this highly complex disease will aid the development of precision therapeutics and improve patient survival. The aim of this study was to determine whether circulating tumour DNA (ctDNA) has...
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