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Article

Gene-specific ctDNA dynamics predict tumour burden and survival outcomes in ESCC: A prospective cohort study.

Clinical and translational medicine - 1 Aug 2025

Gu Rentong, Liu Tao, Cheng Wen, Li Mengxing, Wang Xiaowei, Jin Hai

Abstract excerpt

BACKGROUND: Oesophageal squamous cell carcinoma (ESCC) remains a highly aggressive malignancy with limited biomarkers for monitoring tumour burden and prognosis. Circulating tumour DNA (ctDNA) has emerged as a promising tool for real-time disease assessment, but its clinical utility in ESCC remains underexplored. METHODS: In this prospective cohort study, we analysed preoperative and postoperative ctDNA from 54...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40817602
DOI: 10.1002/ctm2.70446
PMCID: PMC12356824

Genes

PTEN
PIK3CA
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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