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Article

Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma.

British journal of cancer - 1 Feb 2022

Shohdy Kyrillus S, Villamar Dario M, Cao Yen, Trieu Janson, Price Kristin S, Nagy Rebecca, Tagawa Scott T, Molina Ana M, Sternberg Cora N, Nanus David M, Mosquera Juan Miguel, Elemento Olivier, Sonpavde Guru P, Grivas Petros, Vogelzang Nicholas J, Faltas Bishoy Morris

Abstract excerpt

BACKGROUND: Targeted sequencing of circulating tumour DNA (ctDNA) is a promising tool to monitor dynamic changes in the variant allele frequencies (VAF) of genomic alterations and predict clinical outcomes in patients with advanced urothelial carcinoma (UC). METHODS: We performed targeted sequencing of 182 serial ctDNA samples from 53 patients with advanced UC. RESULTS: Serial ctDNA-derived metrics predicted the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35046520
DOI: 10.1038/s41416-021-01648-8
PMCID: PMC8810988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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