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Article

Contribution of Interleukin-4 Genotypes to Lung Cancer Risk in Taiwan.

Anticancer research - 1 Nov 2015

Chang Wen-Shin, Wang Shou-Cheng, Chuang Chin-Liang, Ji Hong-Xue, Hsiao Chieh-Lun, Hsu Chin-Mu, Tsai Chia-Wen, Liu Shih-Ping, Hsu Pei-Chen, Lo Yen-Li, Bau Da-Tian

Abstract excerpt

AIM: Lung cancer is the leading cause of cancer-related death worldwide. Interleukin-4 (IL-4) is a typical pleiotropic T helper 2 cytokine involved in immunology during carcinogenesis. The present study aimed at evaluating the contribution of IL-4 promoter T-1099G (rs2243248), C-589T (rs2243250), C-33T (rs2070874) genetic polymorphisms to the risk of lung cancer in Taiwan. MATERIALS AND METHODS: The contributions...

Topics

Aged
Case-Control Studies
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Follow-Up Studies

Genetic Predisposition to Disease

Genotype

Humans

Interleukin-10

Lung Neoplasms

Male

Middle Aged

Neoplasm Staging

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Prognosis

Promoter Regions, Genetic

Risk Factors

Taiwan

Source

Identifiers

PMID: 26504066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26504066-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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