Article
Growth control and ribosomopathies.
Current opinion in genetics & development - 1 Feb 2013
Teng Teng, Thomas George, Mercer Carol A
Abstract excerpt
Ribosome biogenesis and protein synthesis are two of the most energy consuming processes in a growing cell. Moreover, defects in their molecular components can alter the pattern of gene expression. Thus it is understandable that cells have developed a surveillance system to monitor the status of the translational machinery. Recent discoveries of causative mutations and deletions in genes linked to ribosome...
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