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Article

Immune checkpoint molecules in pregnancy: Focus on regulatory T cells

18 Jan 2020

Abstract excerpt

Regulatory T (Treg) cells are a specialized subpopulation of T cells that plays critical roles in the maintenance of immune homeostasis. Although efforts have been done, their role in human pregnancy is not fully understood. Numerous studies reported the presence of Treg cells throughout gestation by promoting maternal-fetal tolerance and fetal development. Furthermore, Treg population is heterogeneous as it is...

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PMID: 31953958
DOI: 10.1002/eji.201948382

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