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Article

Normal human pregnancy is associated with an elevation in the immune suppressive CD25 + CD4 + regulatory T‐cell subset

16 Apr 2004

Abstract excerpt

Summary CD4+ CD25+ T regulatory cells (TReg), suppress antigen-specific immune responses and are important for allograft tolerance. During pregnancy the mother tolerates an allograft expressing paternal antigens (the fetus) requiring substantial changes in immune regulation over a programmed period of time. We analysed whether immune-suppressive TReg cells were altered during pregnancy and therefore might play a...

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Identifiers

PMID: 15096182
DOI: 10.1111/j.1365-2567.2004.01869.x

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