Article
Circulating tumor DNA as an emerging liquid biopsy biomarker for early diagnosis and therapeutic monitoring in hepatocellular carcinoma.
International journal of biological sciences - 1 Jan 2020
Wu Xiaolin, Li Jiahui, Gassa Asmae, Buchner Denise, Alakus Hakan, Dong Qiongzhu, Ren Ning, Liu Ming, Odenthal Margarete, Stippel Dirk, Bruns Christiane, Zhao Yue, Wahba Roger
Abstract excerpt
As one of the most common malignant tumors worldwide, hepatocellular carcinoma (HCC) is known for its poor prognosis due to diagnosis only in advanced stages. Nearly 50% of the patients with the first diagnosis of HCC die within a year. Currently, the advancements in the integration of omics information have begun to transform the clinical management of cancer patients. Molecular profiling for HCC patients is in...
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