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Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA

30 Jul 2019

Abstract excerpt

Abstract Purpose: Molecular profiling has been used to select patients for targeted therapy and determine prognosis. Noninvasive strategies are critical to hepatocellular carcinoma (HCC) given the challenge of obtaining liver tissue biopsies. Experimental Design: We analyzed blood samples from 206 patients with HCC using comprehensive genomic testing (Guardant Health) of circulating tumor DNA (ctDNA). Results: A...

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Cancer Genomics and Diagnostics
Hepatocellular Carcinoma Treatment and Prognosis
Pancreatic and Hepatic Oncology Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 31363003
DOI: 10.1158/1078-0432.ccr-18-3341

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