Functional associations between polymorphic regions of the human 3'IgH locus and COVID-19 disease.

doi:10.1016/j.gene.2022.146698

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Article

Functional associations between polymorphic regions of the human 3'IgH locus and COVID-19 disease.

Gene - 5 Sept 2022

Colucci Mattia, Frezza Domenico, Gambassi Giovanni, De Vito Francesco, Iaquinta Angela, Massaro Maria Grazia, Di Giambenedetto Simona, Borghetti Alberto, Lombardi Francesca, Panzironi Noemi, Ruggieri Valentino, Giambra Vincenzo, Cianci Rossella

Abstract excerpt

PURPOSE: The pandemic diffusion of Coronavirus Disease 2019 (COVID-19) has highlighted significant gender-related differences in disease severity. Despite several hypotheses being proposed, how the genetic background of COVID-19 patients might impact clinical outcomes remains largely unknown. MET...

Topics

Aged
Aged, 80 and over
Alleles
COVID-19
Enhancer Elements, Genetic
Female
Humans
Immunoglobulin Heavy Chains
Male
Middle Aged
SARS-CoV-2

Source

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Identifiers

PMID: 35772651
DOI: 10.1016/j.gene.2022.146698
PMCID: PMC9241982

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-35772651-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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