Article
Transcriptomic Regulation of Macrophages by Matrix-Bound Nanovesicle-Associated Interleukin-33.
Tissue engineering. Part A - 1 Oct 2022
Cramer Madeline, Pineda Molina Catalina, Hussey George, Turnquist Heth R, Badylak Stephen F
Abstract excerpt
The innate immune response, particularly the phenotype of responding macrophages, has significant clinical implications in the remodeling outcome following implantation of biomaterials and engineered tissues. In general, facilitation of an anti-inflammatory (M2-like) phenotype is associated with tissue repair and favorable outcomes, whereas pro-inflammatory (M1-like) activation can contribute to chronic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.