Article
Macrophage phenotype in response to ECM bioscaffolds.
Seminars in immunology - 1 Feb 2017
Huleihel Luai, Dziki Jenna L, Bartolacci Joseph G, Rausch Theresa, Scarritt Michelle E, Cramer Madeline C, Vorobyov Tatiana, LoPresti Samuel T, Swineheart Ilea T, White Lisa J, Brown Bryan N, Badylak Stephen F
Abstract excerpt
Macrophage presence and phenotype are critical determinants of the healing response following injury. Downregulation of the pro-inflammatory macrophage phenotype has been associated with the therapeutic use of bioscaffolds composed of extracellular matrix (ECM), but phenotypic characterization of macrophages has typically been limited to small number of non-specific cell surface markers or expressed proteins. The...
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