Article
Transcriptome analysis of IL-10-stimulated (M2c) macrophages by next-generation sequencing.
Immunobiology - 1 Jul 2017
Lurier Emily B, Dalton Donald, Dampier Will, Raman Pichai, Nassiri Sina, Ferraro Nicole M, Rajagopalan Ramakrishan, Sarmady Mahdi, Spiller Kara L
Abstract excerpt
Alternatively activated "M2" macrophages are believed to function during late stages of wound healing, behaving in an anti-inflammatory manner to mediate the resolution of the pro-inflammatory response caused by "M1" macrophages. However, the differences between two main subtypes of M2 macrophages, namely interleukin-4 (IL-4)-stimulated "M2a" macrophages and IL-10-stimulated "M2c" macrophages, are not well...
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