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Article

A theory-based practical solution to correct for sex-differential participation bias.

Genome biology - 27 Jun 2022

Lee Hanbin, Han Buhm

Abstract excerpt

Most genomic cohorts are retrospective where the exposures and outcomes are predetermined prior to sample collection. Therefore, a spurious association between an exposure and an outcome can arise if both variables affect study participation. Such concerns were raised in previous studies questioning the representativeness of the UK Biobank. Recently, a genome-wide association study (GWAS) on biological sex found...

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PMID: 35761388
DOI: 10.1186/s13059-022-02703-0
PMCID: PMC9238114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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