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Article

Genetic predictors of participation in optional components of UK Biobank.

Nature communications - 9 Feb 2021

Tyrrell Jessica, Zheng Jie, Beaumont Robin, Hinton Kathryn, Richardson Tom G, Wood Andrew R, Davey Smith George, Frayling Timothy M, Tilling Kate

Abstract excerpt

Large studies such as UK Biobank are increasingly used for GWAS and Mendelian randomization (MR) studies. However, selection into and dropout from studies may bias genetic and phenotypic associations. We examine genetic factors affecting participation in four optional components in up to 451,306 UK Biobank participants. We used GWAS to identify genetic variants associated with participation, MR to estimate...

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Identifiers

PMID: 33563987
DOI: 10.1038/s41467-021-21073-y
PMCID: PMC7873270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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