Article
Isotypic analysis of anti-p53 serum autoantibodies and p53 protein tissue phenotypes in colorectal cancer.
Human pathology - 1 Oct 2022
Islam Roney Mr Md Saiful, Lanagan Ms Catharine, Sheng Yonghua, Gough Ms Madeline, Snell Cameron, Nguyen Nam-Trung, Lawler Karen, Liu Cheng, Lam Alfred King-Yin, Kijanka Gregor Stefan
Abstract excerpt
The presence of IgA- and IgM-specific autoantibody (AAb) isotypes and their relationship to p53 tissue expression patterns are not well understood. This study aims to investigate the clinical utility of the anti-p53 AAb isotypes and tissue positivity in colorectal cancer (CRC). We analyzed anti-p53 IgG, IgM, and IgA AAbs in sera of 99 CRC patients and 99 non-cancer control subjects. Corresponding tissue...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
