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Article

A 10-Year Community-Based Study of Leucine-Rich Repeat Kinase 2 G2385R Carriers' Conversion to Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Aug 2022

Wang Pei, Pan Jing, Luo Qi, Chen Jie, Tang Huidong, Chen Shengdi, Ma Jianfang

Abstract excerpt

BACKGROUND: The G2385R variant of leucine-rich repeat kinase 2 (LRRK2) is mainly associated with Parkinson's disease(PD) in Asian populations. OBJECTIVE: The aim of this study was to investigate the PD conversion rate and clinical characteristics of LRRK2 G2385R nonmanifesting carriers. METHODS: All participants were from the community-based longitudinal cohort of Shanghai Ruijin Hospital. The G2385R carriers and...

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PMID: 35733392
DOI: 10.1002/mds.29127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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