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Article

Obstructive sleep apnea and the risk of Alzheimer's disease and Parkinson disease: A Mendelian randomization study OSA, Alzheimer's disease and Parkinson disease.

Sleep medicine - 1 Sept 2022

Li Jinwei, Zhao Lanqing, Ding Xiaoxu, Cui Xiangguo, Qi Li, Chen Yu

Abstract excerpt

BACKGROUND: Previous studies reported that obstructive sleep apnea (OSA) was associated with neurodegenerative diseases. However, whether these associations are causal are still unsettled. In our study, we investigated the causal effects of genetically-predicted OSA on Alzheimer's disease (AD) and Parkinson disease (PD). METHODS: We implemented two-sample Mendelian randomization to judge causation using summary...

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Identifiers

PMID: 35724440
DOI: 10.1016/j.sleep.2022.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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