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Article

Parkinson’s disease and Alzheimer’s disease: a Mendelian randomization study

1 Dec 2018

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) and Parkinson's disease (PD) are the top two common neurodegenerative diseases in elderly. Recent studies found the α-synuclein have a key role in AD. Although many clinical and pathological features between AD and PD are shared, the genetic association between them remains unclear, especially whether α-synuclein in PD genetically alters AD risk. RESULTS: We did not obtain any...

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PMID: 30598082
DOI: 10.1186/s12881-018-0721-7

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