Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bidirectional Mendelian randomization to explore the causal relationships between Sleep traits, Parkinson's disease and Amyotrophic lateral sclerosis.

Sleep medicine - 1 Aug 2022

Di Hongkun, Zhu Yi, Xia Wenqi, Meng Xin, Zhang Mingye, Xu Minzhi, Feng Jing, Tian Qingfeng, He Yan, Cao Shiyi, Lu Zuxun

Abstract excerpt

OBJECTIVE: Sleep disturbances have been linked with Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) in observational studies, and the comorbidity of PD and ALS has been reported in clinical case reports, but the causalities remain unclear. This study aims to examine bidirectional causal relationships between sleep traits, PD and ALS. METHODS: Bidirectional two sample Mendelian randomisation (MR)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to Causality

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Parkinson Disease

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 35594779
DOI: 10.1016/j.sleep.2022.03.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bidirectional Mendelian randomization to explore the causal relationships between Sleep traits, Parkinson's disease and Amyotrophic lateral sclerosis.PMID 35594779Read ↗

Sleep behaviors and Parkinson's disease: A bidirectional Mendelian randomization analysis.Semantic proximity Read ↗

Exploring the causal association between 6 sleep traits and Parkinson disease.Semantic proximity Read ↗

Rapid eye movement sleep behavior disorder (RBD) and neurodegenerative diseases: A bidirectional 2-sample Mendelian randomization study.Semantic proximity Read ↗

Bidirectional Mendelian randomization study of psychiatric disorders and Parkinson’s diseaseSemantic proximity Read ↗

Evaluating the Bidirectional Causal Association Between Daytime Napping and Alzheimer's Disease Using Mendelian Randomization.Semantic proximity Read ↗

Causal association of gastroesophageal reflux disease with obstructive sleep apnea and sleep-related phenotypes: a bidirectional two-sample Mendelian randomization studySemantic proximity Read ↗

Sleep/wake cycle alterations as a cause of neurodegenerative diseases: A Mendelian randomization studySemantic proximity Read ↗

Obstructive sleep apnea and the risk of Alzheimer's disease and Parkinson disease: A Mendelian randomization study OSA, Alzheimer's disease and Parkinson disease.Semantic proximity Read ↗

Relationship between sleep and progression of Parkinson’s disease – A Mendelian randomization studySemantic proximity Read ↗

Causality between sleep traits and the risk of frailty: a Mendelian randomization studySemantic proximity Read ↗

Causality Investigation between Gut Microbiome and Sleep-Related Traits: A Bidirectional Two-Sample Mendelian Randomization Study.Semantic proximity Read ↗

Understanding Causal Relationships between Imaging-Derived Phenotypes and Parkinson’s Disease: A Mendelian Randomization and Observational StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.