Article
In the Acute Phase of Trypanosoma cruzi Infection, Liver Lymphoid and Myeloid Cells Display an Ambiguous Phenotype Combining Pro- and Anti-Inflammatory Markers.
Frontiers in immunology - 1 Jan 2022
de Lima Pereira Dos Santos Carina, Vacani-Martins Natalia, Cascabulho Cynthia Machado, Pereira Mirian Claudia de Souza, Crispe Ian Nicholas, Henriques-Pons Andrea
Abstract excerpt
Multiple cell populations, cellular biochemical pathways, and the autonomic nervous system contribute to maintaining the immunological tolerance in the liver. This tolerance is coherent because the organ is exposed to high levels of bacterial pathogen-associated molecular pattern (PAMP) molecules from the intestinal microbiota, such as lipopolysaccharide endotoxin (LPS). In the case of Trypanosoma cruzi...
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