Article
Liver accumulation of Plasmodium chabaudi-infected red blood cells and modulation of regulatory T cell and dendritic cell responses.
PloS one - 1 Jan 2013
Medeiros Márcia M, da Silva Henrique B, Reis Aramys S, Barboza Renato, Thompson Joanne, Lima Maria Regina D'Império, Marinho Cláudio R F, Tadokoro Carlos E
Abstract excerpt
It is postulated that accumulation of malaria-infected Red Blood Cells (iRBCs) in the liver could be a parasitic escape mechanism against full destruction by the host immune system. Therefore, we evaluated the in vivo mechanism of this accumulation and its potential immunological consequences. A massive liver accumulation of P. c. chabaudi AS-iRBCs (Pc-iRBCs) was observed by intravital microscopy along with an...
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