Article
Lipid Bodies: Inflammatory Organelles Implicated in Host-Trypanosoma cruziInterplay during Innate Immune Responses
1 Jan 2012
Abstract excerpt
The flagellated protozoa Trypanosoma cruzi is the causal agent of Chagas' disease, a significant public health issue and still a major cause of morbidity and mortality in Latin America. Acute Chagas' disease elicits a strong inflammatory response. In order to control the parasite multiplication, cells of the monocytic lineage are highly mobilized. Monocyte differentiation leads to the formation of phagocytosing...