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Article

Lipid Bodies: Inflammatory Organelles Implicated in Host-Trypanosoma cruziInterplay during Innate Immune Responses

1 Jan 2012

Abstract excerpt

The flagellated protozoa Trypanosoma cruzi is the causal agent of Chagas' disease, a significant public health issue and still a major cause of morbidity and mortality in Latin America. Acute Chagas' disease elicits a strong inflammatory response. In order to control the parasite multiplication, cells of the monocytic lineage are highly mobilized. Monocyte differentiation leads to the formation of phagocytosing...

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PMID: 22619483
DOI: 10.1155/2012/478601

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