Article
Antibody Binding and Angiotensin-Converting Enzyme 2 Binding Inhibition Is Significantly Reduced for Both the BA.1 and BA.2 Omicron Variants.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 8 Feb 2023
Junker Daniel, Becker Matthias, Wagner Teresa R, Kaiser Philipp D, Maier Sandra, Grimm Tanja M, Griesbaum Johanna, Marsall Patrick, Gruber Jens, Traenkle Bjoern, Heinzel Constanze, Pinilla Yudi T, Held Jana, Fendel Rolf, Kreidenweiss Andrea, Nelde Annika, Maringer Yacine, Schroeder Sarah, Walz Juliane S, Althaus Karina, Uzun Gunalp, Mikus Marco, Bakchoul Tamam, Schenke-Layland Katja, Bunk Stefanie, Haeberle Helene, Göpel Siri, Bitzer Michael, Renk Hanna, Remppis Jonathan, Engel Corinna, Franz Axel R, Harries Manuela, Kessel Barbora, Lange Berit, Strengert Monika, Krause Gerard, Zeck Anne, Rothbauer Ulrich, Dulovic Alex, Schneiderhan-Marra Nicole
Abstract excerpt
BACKGROUND: The rapid emergence of the Omicron variant and its large number of mutations led to its classification as a variant of concern (VOC) by the World Health Organization. Subsequently, Omicron evolved into distinct sublineages (eg, BA.1 and BA.2), which currently represent the majority of global infections. Initial studies of the neutralizing response toward BA.1 in convalescent and vaccinated individuals...
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