BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection.

doi:10.1038/s41586-022-04980-y

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Article

BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection.

Nature - 1 Aug 2022

Cao Yunlong, Yisimayi Ayijiang, Jian Fanchong, Song Weiliang, Xiao Tianhe, Wang Lei, Du Shuo, Wang Jing, Li Qianqian, Chen Xiaosu, Yu Yuanling, Wang Peng, Zhang Zhiying, Liu Pulan, An Ran, Hao Xiaohua, Wang Yao, Wang Jing, Feng Rui, Sun Haiyan, Zhao Lijuan, Zhang Wen, Zhao Dong, Zheng Jiang, Yu Lingling, Li Can, Zhang Na, Wang Rui, Niu Xiao, Yang Sijie, Song Xuetao, Chai Yangyang, Hu Ye, Shi Yansong, Zheng Linlin, Li Zhiqiang, Gu Qingqing, Shao Fei, Huang Weijin, Jin Ronghua, Shen Zhongyang, Wang Youchun, Wang Xiangxi, Xiao Junyu, Xie Xiaoliang Sunney

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.2.12.1, BA.4 and BA.5 exhibit higher transmissibility than the BA.2 lineage1. The receptor binding and immune-evasion capability of these recently emerged variants require immediate investigation. Here, coupled with structural comparisons of the spike proteins, we show that BA.2.12.1, BA.4 and BA.5 (BA.4 and BA.5 are hereafter...

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PMID: 35714668
DOI: 10.1038/s41586-022-04980-y
PMCID: PMC9385493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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