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Article

Multiple primary malignances managed with surgical excision: a case report with next generation sequencing analysis.

Molecular biology reports - 1 Sept 2022

Romano Chiara, Di Gregorio Sandra, Pennisi Maria Stella, Tirrò Elena, Broggi Giuseppe, Caltabiano Rosario, Manzella Livia, Ruggieri Martino, Vigneri Paolo, Di Cataldo Antonio

Abstract excerpt

BACKGROUND: Multiple primary malignancies (MPM) are defined as tumors originating in the same individual without any correlation between them. In addition to morphological and immunohistochemical analyses, sensitive DNA sequencing methods such as next generation sequencing (NGS) may help to discriminate the common or different genetic alterations driving each malignancy, to better diagnose these uncommon cases....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35715605
DOI: 10.1007/s11033-022-07630-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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