Somatic Genomic Events in Endometriosis: Review of the Literature and Approach to Phenotyping.

Abstract excerpt

In this review, we provide a survey and appraisal of research into somatic genomic events in endometriosis. Methodologies have evolved from conventional cytogenetics to next-generation sequencing, with findings ranging from chromosome imbalances to recurrent somatic cancer driver mutations. Somatic cancer driver mutations have been described in a range of endometriosis lesions, dominated by recurrent mutations in...

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• Aneuploidy
• Cross-Sectional Studies
• Endometriosis
• Endometrium
• Exome Sequencing