Article
Association of SIRT1 gene polymorphism and its expression for the risk of alcoholic fatty liver disease in the Han population.
Hepatology international - 1 Jan 2018
Hou Yeting, Su Bingzhong, Chen Ping, Niu Haijing, Zhao Sheng, Wang Ruijun, Shen Wei
Abstract excerpt
OBJECTIVE: To investigate the associations between SIRT1 polymorphisms and their expression in patients with alcoholic fatty liver disease (AFLD). METHODS: A total of 268 heavy drinkers were divided into the AFLD group (n = 176) and alcoholic control (n = 92) and 237 light-/non-drinkers into the NAFLD (non-AFLD) group (n = 117) and healthy control (n = 120). The genotyping of SIRT1 (rs33957861, rs11599176,...
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