Article
Insulin-like growth factor binding protein 3 promoter variant (rs2854744) is associated with nonalcoholic fatty liver disease.
Archives of endocrinology and metabolism - 10 Nov 2023
Mahmoudi Touraj, Nouri Shadi, Zarei Fatemeh, Najafabadi Zeinab Nourmohammadi, Sanei Maryam, Sayedsalehi Shiva, Rezamand Gholamreza, Asadi Asadollah, Dabiri Reza, Nobakht Hossein, Farahani Hamid, Tabaeian Seidamir Pasha, Zali Mohammad Reza
Abstract excerpt
Objective: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease and a growing global epidemic. In NAFLD, liver fat surpasses 5% of hepatocytes without the secondary causes of lipid accumulation or excessive alcohol consumption. Given the link between NAFLD and insulin resistance, the possible association between the rs2854744 (-202 G>T) promoter polymorphism of insulin-like growth factor binding...
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