Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ADAR1 Prevents R-loop Accumulation-Driven ATR Pathway Activation in Ovarian Cancer

1 Jan 2022

Abstract excerpt

Adenosine (A)-to-inosine (I) RNA editing is the most prevalent RNA editing mechanism, in which adenosine deaminase acting on RNA 1 (ADAR1) is a major adenosine deaminase. Increasing evidence suggests that editing dysregulation of ADAR1 plays an important role in human tumorigenesis, while the underlying mechanism remains elusive. Here, we demonstrated that ADAR1 was highly expressed in ovarian cancer tissues and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to RNA regulation and disease
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35711824
DOI: 10.7150/jca.72108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ADAR1 Prevents R-loop Accumulation-Driven ATR Pathway Activation in Ovarian CancerPMID 35711824Read ↗

ADAR1 Prevents R-loop Accumulation-Driven ATR Pathway Activation in Ovarian CancerSemantic proximity Read ↗

ADAR, the carcinogenesis mechanisms of ADAR and related clinical applicationsSemantic proximity Read ↗

An RNA editing/binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancerSemantic proximity Read ↗

Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targetsSemantic proximity Read ↗

The role of dsRNA A-to-I editing catalyzed by ADAR family enzymes in the pathogenesesSemantic proximity Read ↗

Functions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human DiseasesSemantic proximity Read ↗

RNA Editing Dynamically Rewrites the Cancer Code.Semantic proximity Read ↗

Identification and characterization of ADAR1 mutations and changes in gene expression in human cancers.Semantic proximity Read ↗

Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensingSemantic proximity Read ↗

Comprehensive Characterization of RNA Editing in Primary Gastric Adenocarcinoma through RNA-seq Data AnalysisSemantic proximity Read ↗

ADARs, RNA editing and more in hematological malignanciesSemantic proximity Read ↗

Genome-wide identification and analysis of A-to-I RNA editing events in the malignantly transformed cell lines from BEP2D induced by α-particles radiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.