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Article

Modification of neutralizing epitopes of hemagglutinin for the development of broadly protective H9N2 vaccine.

Vaccine - 5 Feb 2020

Poh Zhong Wee, Wang Zhenzhang, Kumar Subaschandrabose Rajesh, Yong Hui Yee, Prabakaran Mookkan

Abstract excerpt

The H9N2 avian influenza viruses cause significant economic losses in poultry worldwide and could potentially cause human pandemic. Currently, the available vaccines have limited efficacy due to antigenic drift of H9N2. To improve vaccine efficacy, we developed monovalent vaccine strain via the modification of neutralizing epitopes on hemagglutinin (HA) to broaden the protection against H9N2 viruses. In this...

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Source

Identifiers

PMID: 31924429
DOI: 10.1016/j.vaccine.2019.11.080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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