Article
MC1R variants increase melanoma risk in families with CDKN2A mutations: a meta-analysis.
European journal of cancer (Oxford, England : 1990) - 1 May 2010
Fargnoli Maria Concetta, Gandini Sara, Peris Ketty, Maisonneuve Patrick, Raimondi Sara
Abstract excerpt
AIM OF THE STUDY: We performed a meta-analysis to assess whether MC1R variants increase the risk of melanoma in CDKN2A mutation carriers of melanoma-prone families. METHODS: Data from 96 CDKN2A-positive melanoma-prone families from seven independent populations of Europe, United States and Australia were included in the analysis. Summary risk estimates were calculated by random-effect models. We explored...
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