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Significant role of host sialylated glycans in the infection and spread of severe acute respiratory syndrome coronavirus 2

14 Jun 2022

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been transmitted across all over the world, in contrast to the limited epidemic of genetically- and virologically-related SARS-CoV. However, the molecular basis explaining the difference in the virological characteristics among SARS-CoV-2 and SARS-CoV has been poorly defined. Here we identified that host sialoglycans play a significant role in the...

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PMID: 35700214
DOI: 10.1371/journal.ppat.1010590

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