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The influence of TNIK gene polymorphisms on risperidone response in a Chinese Han population.

Pharmacogenomics - 1 Jul 2022

Xu Qingqing, Li Yaojing, Li Mo, Qin Shengying, Ning Ailing, Yuan Ruixue, Fu Yingmei, Wang Dongxiang, Zhang Ran, Zeng Duan, Yu Wenjuan, Li Huafang, Yu Shunying

Abstract excerpt

Aim: To investigate whether the TNIK gene affects risperidone treatment outcomes in the Chinese population. Methods: A total of 148 unrelated inpatients who received risperidone for six weeks were enrolled. The selected single nucleotide polymorphisms (SNPs; rs2088885, rs7627954 and rs13065441) were genotyped using the MassARRAY® SNP IPLEX platform. Results: The analysis showed that one novel SNP of TNIK,...

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PMID: 35698907
DOI: 10.2217/pgs-2022-0052

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