Article
NTRK2 (TrkB gene) variants and temporal lobe epilepsy: A genetic association study.
Epilepsy research - 1 Nov 2017
Torres Carolina Machado, Siebert Marina, Bock Hugo, Mota Suelen Mandelli, Krammer Bárbara Reis, Duarte Juliana Ávila, Bragatti José Augusto, Castan Juliana Unis, de Castro Luiza Amaral, Saraiva-Pereira Maria Luiza, Bianchin Marino Muxfeldt
Abstract excerpt
OBJECTIVE: The NTRK2 gene encodes a member of the neurotrophic tyrosine kinase receptor family known as TrkB. It is a membrane-associated receptor with signaling and cellular differentiation properties that has been involved in neuropsychiatric disorders, including epilepsy. We report here the frequencies of NTRK2 allele variants in patients with temporal lobe epilepsy (TLE) compared to controls without epilepsy...
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