Article
Neurotrophic tyrosine kinase receptor type 2 (NTRK2) gene associated with treatment response to mood stabilizers in patients with bipolar I disorder.
Journal of molecular neuroscience : MN - 1 Jun 2013
Wang Zuowei, Fan Jinbo, Gao Keming, Li Zezhi, Yi Zhenghui, Wang Lingxiao, Huang Jia, Yuan Chengmei, Hong Wu, Yu Shunying, Fang Yiru
Abstract excerpt
There is increasing evidence supporting the relationship between bipolar disorder (BP) and neurotrophin. The present study investigated the relationship between neurotrophic tyrosine kinase receptor type 2 (NTRK2) gene polymorphisms and bipolar I disorder (BP I) susceptibility and treatment response to mood stabilizers (lithium or valproate). Two-hundred eighty-four patients who met the DSM-IV criteria for BP I...
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