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Article

Unexpected actionable genetic variants revealed by multigene panel testing of patients with uterine cancer.

Gynecologic oncology - 1 Aug 2022

Heald Brandie, Mokhtary Sara, Nielsen Sarah M, Rojahn Susan, Yang Shan, Michalski Scott T, Esplin Edward D

Abstract excerpt

OBJECTIVE: Hereditary uterine cancer (UC) is traditionally associated with pathogenic/likely pathogenic germline variants (PGVs) in Lynch syndrome genes or PTEN; however, growing evidence supports a role for other genes that may reveal new clinical management options. In this study we assessed the prevalence and potential clinical impact of PGVs identified in UC patients referred for comprehensive germline...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35691755
DOI: 10.1016/j.ygyno.2022.05.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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