Article
Up-Front Multigene Panel Testing for Cancer Susceptibility in Patients With Newly Diagnosed Endometrial Cancer: A Multicenter Prospective Study.
JCO precision oncology - 1 Nov 2021
Levine Monica D, Pearlman Rachel, Hampel Heather, Cosgrove Casey, Cohn David, Chassen Alexis, Suarez Adrian, Barrington David A, McElroy Joseph P, Waggoner Steven, Nakayama John, Billingsley Caroline, Resnick Kim, Andrews Stephen, Singh Sareena, Jenison Eric, Clements Aine, Neff Robert, Goodfellow Paul J
Abstract excerpt
PURPOSE: Clinical utility of up-front multigene panel testing (MGPT) is directly related to the frequency of pathogenic variants (PVs) in the population screened and how genetic findings can be used to guide treatment decision making and cancer prevention efforts. The benefit of MGPT for many common malignancies remains to be determined. In this study, we evaluated up-front MGPT in unselected patients with...
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