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Article

KRAS gene mutations - prognostic factor in colorectal cancer?

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2015

Dobre Maria, Dinu Daniela Elena, Panaitescu Eugenia, Bîrlă Rodica Daniela, Iosif Cristina Ileana, Boeriu Marius, Constantinoiu Silviu, Ivan Roxana Nicoleta, Ardeleanu Carmen Maria, Costache Marieta

Abstract excerpt

The colorectal cancer (CRC) modern therapy is using adjuvant and neoadjuvant companion therapeutic agents, part of them having an anti-angiogenic action. Their benefic effect can be annulated by some gene mutations, which are interfering in signal transduction pathways. One of the more frequent activating mutations is occurring in the KRAS gene. We assessed the KRAS mutations by two molecular methods, in a group...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Proto-Oncogene Proteins p21(ras)

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Identifiers

PMID: 26429158

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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