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Article

SIRT6 promotes mitochondrial fission and subsequent cellular invasion in ovarian cancer

10 Jun 2022

Abstract excerpt

Ovarian cancer ranks fifth in terms of cancer mortality in women due to lack of early diagnosis and poor clinical management. Characteristics like high cellular proliferation, EMT and metabolic alterations contribute to oncogenicity. Cancer, being a “metabolic disorder,” is governed by various key regulatory factors like metabolic enzymes, oncogenes, and tumor suppressors. Sirtuins (SIRT1‐SIRT7) belong to the...

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PMID: 35686673
DOI: 10.1002/2211-5463.13452

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