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SIRT7 Exhibits Oncogenic Potential in Human Ovarian Cancer Cells

29 Apr 2015

Abstract excerpt

BACKGROUND: Sirtuin7 (SIRT7) is a type of nicotinamide adenine dinucleotide oxidized form (NAD+)-dependent deacetylase and the least understood member of the sirtuins family; it is implicated in various processes, such as aging, DNA damage repair and cell signaling transduction. There is some evidence that SIRT7 may function as a tumor trigger for human malignancy. Here, we aimed to explore the biological...

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PMID: 25921180
DOI: 10.7314/apjcp.2015.16.8.3573

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