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Article

Methylation marker analysis and HPV16/18 genotyping in high-risk HPV positive self-sampled specimens to identify women with high grade CIN or cervical cancer.

Gynecologic oncology - 1 Oct 2014

Verhoef Viola M J, Heideman Daniëlle A M, van Kemenade Folkert J, Rozendaal Lawrence, Bosgraaf Remko P, Hesselink Albertus T, Bekkers Ruud L M, Massuger Leon F A G, Steenbergen Renske D M, Snijders Peter J F, Berkhof Johannes, Meijer Chris J L M

Abstract excerpt

OBJECTIVES: Methylation marker analysis using bi-marker panel MAL/miR-124-2 is a promising triage test for identifying cervical (pre)cancer in high-risk human papillomavirus (hrHPV) positive women. Bi-marker panel MAL/miR-124-2 can be applied directly on self-sampled cervico-vaginal material and its sensitivity is non-inferior to that of cytology, yet at the cost of more colposcopy referrals. Our objective was to...

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Identifiers

PMID: 25111387
DOI: 10.1016/j.ygyno.2014.08.003

Genes

MAL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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