Article
Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16/18 genotyping for the detection of cervical (pre)cancer in high-risk HPV-positive women of a gynecologic outpatient population (COMETH study).
International journal of cancer - 15 Feb 2016
Luttmer Roosmarijn, De Strooper Lise M A, Berkhof Johannes, Snijders Peter J F, Dijkstra Maaike G, Uijterwaal Margot H, Steenbergen Renske D M, van Kemenade Folkert J, Rozendaal Lawrence, Helmerhorst Theo J M, Verheijen Rene H M, Ter Harmsel W Abraham, Van Baal W Marchien, Graziosi Peppino G C M, Quint Wim G V, Heideman Daniëlle A M, Meijer Chris J L M
Abstract excerpt
Recently, DNA methylation analysis of FAM19A4 in cervical scrapes has been shown to adequately detect high-grade cervical intraepithelial neoplasia and cervical cancer (≥ CIN3) in high-risk HPV (hrHPV)-positive women. Here, we compared the clinical performance of FAM19A4 methylation analysis to c...
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