Article
Association of LXRα polymorphisms with obesity and obesity-related phenotypes in an Iranian population.
Annals of human biology - 1 Jan 2000
Rooki Hassan, Ghayour-Mobarhan Majid, Pourhosseingholi Mohamad-Amin, Azarpazhooh Mahmoud-Reza, Ebrahimi Mahmoud, Ferns Gordon, Zali Mohammad-Reza
Abstract excerpt
BACKGROUND: Obesity is a multifactorial disorder due to the complex interaction between genetic and environmental factors. Liver X receptor alpha (LXRα), encoded by the gene NR1H3, is involved in lipoprotein metabolism and its genetic variations may also play a role in the aetiology of obesity. AIM: To assess the association of two NR1H3 polymorphisms (rs11039155 and rs2279238) and their haplotypes with obesity...
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