Article
ASCO/SSO review of current role of risk-reducing surgery in common hereditary cancer syndromes.
Annals of surgical oncology - 1 Oct 2006
Guillem José G, Wood William C, Moley Jeffrey F, Berchuck Andrew, Karlan Beth Y, Mutch David G, Gagel Robert F, Weitzel Jeffrey, Morrow Monica, Weber Barbara L, Giardiello Francis, Rodriguez-Bigas Miguel A, Church James, Gruber Stephen, Offit Kenneth
Abstract excerpt
BACKGROUND: A significant portion of cancers are accounted for by a heritable component, which has increasingly been linked to mutations in specific genes. Clinical interventions have been formulated for mutation carriers within affected families. The primary interventions for mutation carriers of highly penetrant syndromes are surgical. METHODS: The American Society of Clinical Oncology and the Society of...
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