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Article

Identification of Patients at Elevated Cancer Risk through a Community-Based Genetic Testing Program.

Annals of surgical oncology - 1 Nov 2025

Brabender Danielle, Siegel Emily, Culver Julie O, Comeaux Jacob G, Date Anjali, Woodworth Amanda

Abstract excerpt

BACKGROUND: Only a subset of individuals meeting National Comprehensive Cancer Network (NCCN) guidelines for genetic screening of hereditary cancers are being offered testing. A community-based screening program has the potential to expand access, identify critical screening opportunities among those testing positive, and have potential downstream clinical effects. METHODS: We conducted a retrospective review of...

Topics

Humans
Female
Genetic Testing
Retrospective Studies
Middle Aged
Genetic Predisposition to Disease
Early Detection of Cancer
Mammography
Aged
Prognosis
Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Adult

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Identifiers

PMID: 40770526
DOI: 10.1245/s10434-025-17820-w
PMCID: PMC12534363

Genes

APC
BRCA2
CHEK2
MUTYH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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