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Structure of Human TMPRSS2 in Complex with SARS-CoV-2 Spike Glycoprotein and Implications for Potential Therapeutics

8 Jun 2022

Abstract excerpt

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 520 million people around the globe resulting in more than 6.2 million as of May 2022. Understanding the cell entry mechanism of SARS-CoV-2 and its entire repertoire is a high priority for developing improved therapeutics. The SARS-CoV-2 spike glycoprotein (S-protein)...

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PMID: 35675654
DOI: 10.1021/acs.jpclett.2c00967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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