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Article

DPEP1 promotes drug resistance in colon cancer cells by forming a positive feedback loop with ASCL2

6 Jun 2022

Abstract excerpt

BACKGROUND: Drug resistance is an important factor affecting the efficacy of chemotherapy in patients with colon cancer. However, clinical markers for diagnosing drug resistance of tumor cells are not only a few in number, but also low in specificity, and the mechanism of action of tumor cell drug resistance remains unclear. METHODS: Dipeptidase 1 (DPEP1) expression was analyzed using the cancer genome atlas...

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PMID: 35670012
DOI: 10.1002/cam4.4926

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